Prospective Hemodynamic and Pharmacokinetic Analysis of Oxymetazoline Absorption
Completed · Not applicable
Conditions studied: Adenoidectomy, Functional Endoscopic Sinus Surgery (FESS), Turbinate Surgery
In brief
This proposed study will assess the hemodynamic effects and measure the systemic absorption of topically applied oxymetazoline in patients undergoing functional endoscopic sinus surgery, turbinate surgery, or adenoidectomy. These patients will be receiving oxymetazoline as standard of care during the surgery.
Key facts
- Study ID
- NCT02453841
- Run by
- Richard Cartabuke
- People needed
- 30
- Starts
- 2015-12-01
- Expected to finish
- 2017-04-20
- Last updated by the study team
- 2018-09-18
Who can join
Age: 2 and older, up to 18. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Patients that are scheduled for:
- Functional endoscopic sinus surgery
- Turbinate reduction (with or without tonsillectomy and/or adenoidectomy)
- Adenoidectomy
You may not qualify if…
- Been treated with oral decongestants or antihistamines within 24 hours of surgery
- Are taking anticoagulants
- Have a history of nasal trauma
- Have a history of epistaxis
- Have a history of hypertension or cardiac disease
- Allergy to oxymetazoline
Where it is running
- Nationwide Children's Hospital — Columbus, Ohio, United States
Full record on ClinicalTrials.gov
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