Do Arterial Catheters Reduce the Risk of Major Perioperative Complications

Completed · Not applicable

Conditions studied: Postoperative Complications

In brief

Even slight reduction in serious complications related to blood pressure management would easily justify the cost and relatively rare complications consequent to arterial catheter insertion. However, it seems unlikely that major outcomes will be improved by the presumably slight difference in hemodynamic control resulting continuous blood pressure measurement rather than measurements at 2-5-minute intervals. There is considerable variation in practice and no clear consensus whether arterial lines should be placed or not, especially in ASA 2 patients undergoing major non-cardiac surgery or ASA-3 patients undergoing moderate to major non-cardiac surgery. Clearly, if there is no benefit to outcome, arterial lines, which are invasive and costly, should not be placed routinely. The investigators therefore propose to test the primary hypothesis that use of arterial catheters decreases the risk of a collapsed composite of in-hospital mortality, re-admissions, MINS, AKI, stroke, respiratory and wound healing and gastro-intestinal complications after non-cardiac surgery. Secondarily, the investigators propose to test the hypotheses that arterial catheter use: 1) decreases the duration of hospitalization; 2) increases blood gas, electrolyte, and coagulation testing; 3) increases induction-to-incision time; and, 4) increases cost-of-care (supplies,, blood tests, and induction-to-incision time).

Key facts

Study ID

NCT02453815

Run by

The Cleveland Clinic

People needed

286

Starts

2015-06-01

Expected to finish

2020-01-24

Last updated by the study team

2020-01-28

Who can join

Age: 18 and older, up to 90. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• ASA Physical Status 2-4 patients
• inpatient non-cardiac surgery
• radial arterial catheter might or might not reasonably be used based on co-morbidity or type of surgery.

You may not qualify if…

• the attending anesthesiologist requires or refuses an arterial catheter
• already have an arterial catheter
• catheter is contraindicated
• end-stage renal disease
• abnormal Allen's test
• known radial arterial pathology

Where it is running

• Cleveland Clinic — Cleveland, Ohio, United States

Full record on ClinicalTrials.gov

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