Etiology of the Platelet-Cancer Metastatic Pathway - A Study of Inflammatory Markers, Platelet Characteristics and Metastatic Surrogates in Cancer Patients and Controls
Status unconfirmed · Not applicable
Conditions studied: Neoplasm
In brief
The purpose of this research study is to understand if platelets in the blood become more active during cancer and specially advanced stages of cancer, in the future the investigators want to see if reducing platelet activity can improve survival in advanced cancer.
Key facts
- Study ID
- NCT02450175
- Run by
- Sinai Hospital of Baltimore
- People needed
- 50
- Starts
- 2014-06-01
- Expected to finish
- 2016-06-01
- Last updated by the study team
- 2015-05-21
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: accepted.
You may qualify if…
- Cases:
- 25 adult patients (>18 years old) with any form of metastatic or advanced stage (TNM stage III or equivalent) solid adenocarcinoma including breast, colon, and lung cancer will be eligible for inclusion in this study with no restrictions related to previous chemotherapy, radiotherapy, biological therapy or surgical management at the time of enrollment or in the past., although we will prefer to recruit them prior to initiating chemotherapy.
- Controls:
- 25 patients will be selected based on age (+/- 5 years), sex and ethnicity matches from the outpatient medicine Clinic at Sinai hospital, as well as the Sinai community care clinic.
You may not qualify if…
- Thrombocytopenia, defined as a platelet count of <100,000 at the time of
- recruitment of in the last available laboratory data
- History of known bleeding disorder or known platelet dysfunction
- Patients on antiplatelet treatment or anticoagulant therapies at the time of enrollment or 10 days prior to testing
- CKD stage IV or greater
Where it is running
- SInai Hospital of Baltimore, Inc. — Baltimore, Maryland, United States (enrolling)
Full record on ClinicalTrials.gov
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