Evaluation of Repeat Administration of Purified Poloxamer 188
Completed · Phase 3
Conditions studied: Sickle Cell Disease
In brief
The purpose of this study is to evaluate the safety of repeat administration of MST-188 during vaso-occlusive crisis of sickle cell disease. Additionally, this study will evaluate the development of acute chest syndrome during VOC and re-hospitalization for recurrence of VOC.
Key facts
- Study ID
- NCT02449616
- Run by
- Mast Therapeutics, Inc.
- People needed
- 16
- Starts
- 2015-06-01
- Last updated by the study team
- 2016-10-28
Who can join
Age: 4 and older, up to 65. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Completed participation in study MST-188-01 (EPIC study)
- Subject age 4 through 65 years
- Subject is experiencing acute pain typical of VOC and requires treatment with parenteral opioid analgesia
- Subject requires hospitalization
You may not qualify if…
- Subject has acute chest syndrome
- Subject's laboratory results indicate inadequate organ function
- Subject is pregnant or nursing an infant
- Subject had a painful crisis requiring hospitalization within the preceding 14 days
- Subject has been transfused within the past 14 days
- Subject has complications related to SCD
Where it is running
- Rady Children's Hospital — San Diego, California, United States
- Children's Hospital of Southwest Florida — Fort Myers, Florida, United States
- Joe Dimaggio Children's Hospital — Hollywood, Florida, United States
- Ann and Robert H. Lurie Children's Hospital of Chicago — Chicago, Illinois, United States
- University of Iowa Children's Hospital — Iowa City, Iowa, United States
- Our Lady of the Lake Children's Hospital — Baton Rouge, Louisiana, United States
- Rutgers University — New Brunswick, New Jersey, United States
- Medical University of South Carolina — Charleston, South Carolina, United States
- T. C. Thompson Children's Hospital — Chattanooga, Tennessee, United States
Full record on ClinicalTrials.gov
Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.