Study of Methodologies to Measure Blood Flow and Oxygenation in Adults With Sickle Cell Disease

Completed

Conditions studied: Healthy, Sickle Cell Disease

In brief

The purpose of the study is to determine whether imaging techniques, such as magnetic resonance imaging (MRI), near infrared spectroscopy (NIRS), laser speckle contrast imaging (LSCI), and optical imaging (OI), can detect differences in blood flow and oxygen levels in different organ systems of participants with sickle cell disease (SCD). Differences in blood flow and oxygen levels detected by these techniques will be evaluated to determine their utility as biomarkers of clinical disease pathophysiology.

Key facts

Study ID
NCT02447627
Run by
Bioverativ Therapeutics Inc.
People needed
38
Starts
2015-06-01
Expected to finish
2016-10-01
Last updated by the study team
2020-12-19

Who can join

Age: 18 and older, up to 45. Sex: any. Healthy volunteers: accepted.

Where it is running

Full record on ClinicalTrials.gov

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