HDL Lipidomic, Proteomic and Functional Changes in Women After Eating Eggs

Completed · Not applicable

Conditions studied: Overweight, Obesity

In brief

The objective of this randomized, single blinded cross-over study is to investigate effects of daily egg versus yolk-free egg substitute consumption on High Density Lipoprotein (HDL) composition and function in a population of overweight and obese postmenopausal women.

Key facts

Study ID

NCT02445638

Run by

University of California, Davis

People needed

20

Starts

2015-05-01

Expected to finish

2017-09-06

Last updated by the study team

2019-01-24

Who can join

Age: 45 and older, up to 70. Sex: female. Healthy volunteers: accepted.

You may qualify if…

• Female
• 45-70 years old
• Overweight or obese (BMI 25-35 kg/m2)
• Post-menopausal (confirmed by clinical hormone levels assessed at screening if within one year of last menses)
• Plasma HDL cholesterol greater than or equal to 50 mg/dL.

You may not qualify if…

• Documented chronic diseases including diabetes, thyroid disease, metabolic syndrome, cancer (active), or previous cardiovascular events
• Having 3 or more traits of Metabolic Syndrome
• Egg allergy or multiple food allergies or food intolerances that would significantly limit food intake
• Smoker
• Current consumption more than 1 alcoholic drink/ day
• Extreme dietary or exercise patterns
• Recent weight fluctuations (greater than 10% in the last six months)
• Anemia
• Taking prescription lipid medications or other supplements known to alter lipoprotein metabolism such as isoflavones, red yeast rice, or > 1 g of fish oil/day.
• Taking exogenous hormones (i.e. hormone replacement therapy)

Where it is running

• University of California, Davis — Davis, California, United States

Full record on ClinicalTrials.gov

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