Evaluation of Zimmer Puros® Allograft vs. Creos™ Allograft for Alveolar Ridge Preservation
Completed · Not applicable
Conditions studied: Alveolar Bone Grafting, Allograft, Dental Extraction, Dental Implant, Socket Preservation
In brief
The purpose of this study is to evaluate clinically, histologically and radiographically the healing of extraction sockets with Zimmer's Puros® allograft compared to creos™ (creo™ Nobel Biocare,), a low-cost allograft material, 90 days following exodontia.
Key facts
- Study ID
- NCT02444052
- Run by
- University of Florida
- People needed
- 15
- Starts
- 2015-10-01
- Expected to finish
- 2017-10-01
- Last updated by the study team
- 2018-04-02
Who can join
Age: 21 and older, up to 75. Sex: any. Healthy volunteers: accepted.
You may qualify if…
- Systemically healthy subjects with two non-adjacent molar or premolar teeth located in the same jaw that require extraction and socket augmentation for implant site development (treatment sites may be located in either the mandibular or maxillary jaw)
- Residual extraction sockets must have <70% bone loss in all dimensions (3 or 4-walled bony defects)
- Nonsmokers (individuals who quit smoking at least 6 months prior to the study will be allowed to participate)
- Subjects willing and able to comply with all study-related procedures including maintenance of good oral hygiene and compliance with re-evaluation appointments
- Subjects who read, understand and are willing to sign an informed consent statement.
You may not qualify if…
- Inadequate zone of keratinized gingiva (KG) or alveolar mucosa to obtain primary wound closure of the surgical site
- Presence of acute infections at the time of tooth extraction
- Clinically significant or unstable (as defined by the investigators) systemic diseases affecting bone or soft tissue growth; or other renal, hepatic, cardiac, endocrine, hematologic, autoimmune or acute infectious diseases that makes interpretation of the data more difficult
- History of head \& neck radiation therapy
- Subjects taking steroids, tetracycline or tetracycline analogs, bone therapeutic levels of fluorides, biphosphonates, medications affecting bone turnover, antibiotics for >7 days or any investigational drug
- Patients who are or become pregnant during the length of the study.
Where it is running
- University of Florida College of Dentistry-Periodontics — Gainesville, Florida, United States
Full record on ClinicalTrials.gov
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