Memory and Exercise Training Study in Older Adults With Subjective Memory Complaints
Completed · Not applicable
Conditions studied: Memory Impairment
In brief
This pilot study is a first step in a rapidly growing area of clinical research to create the most effective means to combat age-related losses in cognitive function through preventive lifestyle strategies such as physical exercise and memory training. This study will develop innovative simultaneous exercise and memory training programs in non-demented volunteers with subjective memory complaints (controls or MCI). Our primary goal is to assess the cognitive impact of 4-week memory training programs done twice weekly: 1. during simultaneous aerobic exercise (SIM-AR-MET), 2. sequentially after aerobic exercise (SEQ-AR-MET), or 3. without aerobic exercise (replaced with sequential stretching and toning) (SEQ-ST-MET). The investigators will also measure potential metabolic (e.g., glucose, lipid panel) and molecular (serum BDNF) mediators of observed cognitive changes in a subset of participants (those at the UCLA CTRC/IPCN site).
Key facts
- Study ID
- NCT02433691
- Run by
- David Merrill, MD, PhD
- People needed
- 60
- Starts
- 2015-01-01
- Expected to finish
- 2017-06-01
- Last updated by the study team
- 2018-05-02
Who can join
Age: 60 and older, up to 75. Sex: any. Healthy volunteers: accepted.
You may qualify if…
- In good health
- Have memory problems or complaints
- Living independently
You may not qualify if…
- History of neurodegenerative disease or dementia
- Major psychiatric conditions
- Neurological disorders
- Active alcohol or substance abuse
- Head trauma or systemic diseases affecting brain function
- Uncontrolled hypertension or cardiovascular disease
Where it is running
- UCLA Longevity Center — Los Angeles, California, United States
Full record on ClinicalTrials.gov
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