Short vs Long Duration Dual Antiplatelet Therapy in Patients Undergoing Lower Extremity Endovascular Revascularization
Withdrawn before enrolling · Phase 3
Conditions studied: Peripheral Arterial Disease, Endovascular Procedures
In brief
The primary objective of the trial is to evaluate short versus long duration dual antiplatelet therapy in patients undergoing lower extremity endovascular revascularization.
Key facts
- Study ID
- NCT02433587
- Run by
- University Hospitals Cleveland Medical Center
- People needed
- 0
- Starts
- 2019-10-01
- Expected to finish
- 2023-07-01
- Last updated by the study team
- 2019-10-07
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Provide signed informed consent before initiation of any study related procedures
- Be at least 18 years of age
- Successful percutaneous lower extremity (iliac and infrainguinal) endovascular revascularization (percutaneous transluminal angioplasty, and /or stent).
- At least 1 vessel run-off in segment distal to the intervention
- Rutherford Classification 2-5 that is unresponsive to medical therapy
You may not qualify if…
- Acute limb ischemia
- Procedure includes device deployment that has specific FDA regulations for anticoagulation/anti-platelet medication regimen.
- Patient undergoing atherectomy procedure
- Intervention includes deployment of drug eluted stent
- Critical limb ischemia (Rutherford Classification 6)
- Thrombocytopenia: Platelet count <50k
- Liver disease (Childs-Pugh B or C)
- Existing need for on going clopidogrel therapy
- Proton Pump Inhibitor Use (If unable to be switched)
- Need for therapeutic anticoagulation
- Known hypercoagulable disorder
- Allergy or contraindication to aspirin or clopidogrel
- Pregnancy
- Patients enrolled in another investigational drug or device study within the past 30 days
Where it is running
- University Hospitals Case Medical Center — Cleveland, Ohio, United States
Full record on ClinicalTrials.gov
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