The Efficacy of a Depression Intervention for Adolescents With Depression and Sleep Disturbances
Completed · Not applicable
Conditions studied: Depression
In brief
The focus of this study is on identifying how Interpersonal Psychotherapy for Adolescents (IPT-A) with depression works to change sleep and related biological markers found in saliva, namely cortisol and pro-inflammatory cytokine levels. The long-term goal of this project is to understand the biological mechanisms of recovery from depression in order to assist in selecting and guiding personalized psychotherapeutic interventions with the highest likelihood of success for individual adolescents with depression.
Key facts
- Study ID
- NCT02429674
- Run by
- New York State Psychiatric Institute
- People needed
- 14
- Starts
- 2015-02-01
- Expected to finish
- 2021-01-01
- Last updated by the study team
- 2021-02-01
Who can join
Age: 12 and older, up to 17. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- outpatient participant
- parent or legally authorized representative must provide consent and assent by the participant
- Diagnostic and Statistical Manual of Mental Disorders Fifth Edition (DSM-V) criteria for a depressive disorder
- Clinical Global Assessment Scale (C-GAS) < 65
- Quick Inventory of Depression Symptoms - Self Report 16 (QIDS-SR16) over 8 and less than 24.
- English speaking
- significant sleep complaints
You may not qualify if…
- co-morbid psychiatric diagnosis of bipolar disorder, psychosis, autism spectrum disorder, intellectual development disorder, conduct disorder or substance abuse disorder
- any condition or illness such as uncontrolled seizure disorder, uncontrolled diabetes, or any other conditions that represent as an inappropriate risk to the participant and/or could confound the interpretation of the study
- currently in active evidence-based psychotherapy for the same condition
- currently taking medication for a psychiatric diagnosis that is not a stable dose (4 weeks on the same dose).
- currently considered at risk for suicide in the opinion of the study doctor, has made a suicide attempt in the past 4 months, or is currently reporting active suicidal ideation.
- history of alcohol or other substance abuse as defined by DSM-V within the last 6 months.
- evidence from clinical diagnosis or report by youth or parent of sleep apnea, restless legs or periodic limb movements during sleep
- sleep treatment that might confound the interpretation of sleep outcomes.
Where it is running
- Pediatric Anxiety and Mood Research Clinic, New York State Psychiatric Institute — New York, New York, United States
Full record on ClinicalTrials.gov
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