The Effect of Prefrontal Cortex Stimulation on Antisocial and Aggressive Behavior

Completed · Not applicable · Has a placebo group

Conditions studied: Antisocial Behavior, Aggression

In brief

This study investigates the effect of upregulating prefrontal cortex activity on antisocial and aggressive behavior and risk factors for such behavior. In the double-blind, randomized controlled trial, participants will undergo anodal transcranial direct current stimulation bilaterally to the dorsolateral prefrontal cortex or a sham stimulation. During and after stimulation, they will complete survey and laboratory measures assessing antisocial and aggressive behavior and risk factors for antisocial and aggressive behavior. Heart rate and skin conductance will also be measured.

Key facts

Study ID

NCT02427672

Run by

University of Pennsylvania

People needed

84

Starts

2015-03-01

Expected to finish

2018-12-01

Last updated by the study team

2019-08-28

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Above 18 years of age
• Able to understand the nature of the study and give informed consent

You may not qualify if…

• History of or active neurologic, cardiovascular, or psychiatric disease
• Currently consuming anti-convulsant, anti-psychotic, or sedative/hypnotic medications
• Currently consuming anti-depressants
• History of seizures
• Metallic implants on the scalp
• Participation in other transcranial magnetic stimulation (TMS) or tDCS experiments on the same day
• History of adverse reactions to tDCS

Where it is running

• University of Pennsylvania — Philadelphia, Pennsylvania, United States

Full record on ClinicalTrials.gov

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