Human Prostate Tissue Model to Maintain and Study Prostate Cancer Stem Cells

Completed

Conditions studied: Benign Prostatic Hyperplasia, Prostate Carcinoma

In brief

This pilot research trial studies the use of a human prostate tissue model to maintain and study prostate cancer stem cells. A human prostate tissue model uses leftover tissue that was removed during surgery from patients with non-cancerous enlargement of the prostate (benign prostatic hyperplasia) and may create an environment similar to the natural environment of the human body. Prostate cancer stem cells are cells that cause cancer to grow. Using real tissue to create an environment to study stem cells may help doctors learn more about how they work and how they respond to treatments.

Key facts

Study ID

NCT02425800

Run by

Wake Forest University Health Sciences

People needed

43

Starts

2015-07-28

Expected to finish

2021-08-03

Last updated by the study team

2021-09-01

Who can join

Age: any. Sex: male. Healthy volunteers: not accepted.

You may qualify if…

• Male patients scheduled for a prostatectomy
• Ability to understand and the willingness to sign an Institutional Review Board (IRB)-approved informed consent document

You may not qualify if…

• Patients with prostate involvement secondary and as a result of metastasis or spread of cancerous cells from other organs

Where it is running

• Comprehensive Cancer Center at Wake Forest University — Winston-Salem, North Carolina, United States
• Comprehensive Cancer Center of Wake Forest University — Winston-Salem, North Carolina, United States

Full record on ClinicalTrials.gov

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