MRE Consumption and Gut Health
Completed · Not applicable
Conditions studied: Gastrointestinal Tract
In brief
The objective of this study is to determine the impact of consuming MREs as the sole source of subsistence for 21 days on gut bacteria community composition and gut health. Up to 80 free-living adults will be randomized to consume their usual diet or only MREs for 21 consecutive days. MREs will be provided by the Military Nutrition Division, US Army Research Institute of Environmental Medicine (USARIEM). Fecal, urine and blood samples will be collected periodically before, during and after the intervention to measure gut barrier integrity, gut bacteria community composition, and markers of gut health, inflammation, and nutritional status.
Key facts
- Study ID
- NCT02423551
- Run by
- United States Army Research Institute of Environmental Medicine
- People needed
- 71
- Starts
- 2015-04-01
- Expected to finish
- 2017-02-01
- Last updated by the study team
- 2019-04-16
Who can join
Age: 18 and older, up to 62. Sex: any. Healthy volunteers: accepted.
You may qualify if…
- BMI </= 30
You may not qualify if…
- Use of antiobiotcs within 3 months of study participation
- Use of pro- or prebiotic supplements within 2 weeks of study participation
- Vegetarian diets
- Use of laxatives, stool softeners, or anti-diarrheal medications at least once a week.
- Fewer than 4 bowel movements, on average, per week
- History of gastrointestinal disease
- Colonoscopy within 3 months of study participation
- Food allergies or aversions or other issues with foods that would preclude MRE consumption, including gluten, milk, nuts, or eggs.
- Use non-steroidal anti-inflammatory medications (NSAIDs) or antihistamine prescribed by a physician or clinician, or unwillingness to discontinue the use of these substances during the study.
- Actively trying to lose weight
- Pregnant or lactating
- Recent blood donation
Where it is running
- USARIEM — Natick, Massachusetts, United States
Full record on ClinicalTrials.gov
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