DISCOVER Study: Microscope-integrated Intraoperative OCT Study

Completed

Conditions studied: Retinal Diseases, Fuchs Endothelial Dystrophy, Macular Hole, Epiretinal Membrane, Retinal Detachment

In brief

Optical coherence tomography (OCT )provides high resolution information regarding the anatomic structure of the tissues of the eye in a cross-sectional and 3 dimensional view. Much of this information is not able to be visualized by a clinician. Utilizing this information during surgery will allow for the ophthalmic surgeons to better understand how surgical procedures impact the anatomic structure of the eye. In this study an OCT device that has been built into the microscope (rather than mounted on the side or held in the surgeon's hand) and will be utilized to take images at various milestones during surgery to assess feasibility and potential utility of this technology. Since it is built into the microscope, there are potential significant advantages over a separate system including increased efficiency, improved working distance, and the ability to visualize tissue-instrument interactions.

Key facts

Study ID

NCT02423213

Run by

The Cleveland Clinic

People needed

2911

Starts

2014-01-01

Expected to finish

2026-06-01

Last updated by the study team

2026-08-03

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• The study population includes any patient requiring ophthalmic surgery

You may not qualify if…

• Under the age of 18 years.
• Cognitive/Mentally impaired or unable to provide consent

Where it is running

• Cole Eye Institute, Cleveland Clinic — Cleveland, Ohio, United States

Full record on ClinicalTrials.gov

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