Inflammation-Induced CNS Glutamate During Breast Cancer Treatment

Completed

Conditions studied: Breast Cancer

In brief

The purpose of this study is to try and provide data linking the impact of increased inflammatory cytokines as a result of chemotherapy and their relationship with increased levels of CNS glutamate and related behavioral and cognitive consequences in breast cancer patients. The investigators will use neuropsychiatric assessments, blood sampling and Magnetic Resonance Spectroscopy (MRS) to collect study data.

Key facts

Study ID

NCT02421978

Run by

Emory University

People needed

98

Starts

2015-05-01

Expected to finish

2018-05-29

Last updated by the study team

2019-08-01

Who can join

Age: 21 and older, up to 65. Sex: female. Healthy volunteers: accepted.

You may qualify if…

• Female breast cancer patients will have undergone surgery (lumpectomy or mastectomy) with or without neoadjuvant or adjuvant chemotherapy
• Age between 21-65 years

You may not qualify if…

• Taking trastuzumab

Where it is running

• Emory University Department of Psychiatry and Behavioral Sciences — Atlanta, Georgia, United States

Full record on ClinicalTrials.gov

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