Pragmatic Airway Resuscitation Trial

Completed · Not applicable

Conditions studied: Cardiac Arrest

In brief

The primary objective of the trial is to determine if 72-hour survival after out-of-hospital cardiac arrest (OHCA) is improved with initial endotracheal intubation (ETI) over initial laryngeal tube (LT) airway management strategies.

Key facts

Study ID

NCT02419573

Run by

University of Alabama at Birmingham

People needed

3004

Starts

2015-12-01

Expected to finish

2017-12-01

Last updated by the study team

2019-01-14

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Out-of-hospital cardiac arrest (OHCA)
• Adult (age ≥18 years or per local interpretation)
• Non-traumatic etiology
• Initiation of ventilatory support (e.g., bag-valve-mask device, non-rebreather mas, etc.)

You may not qualify if…

• Known pregnant women
• Known prisoners
• Major facial trauma (visible major deformity, copious oral bleeding, etc)
• Major bleeding or exsanguination (e.g., major upper or lower GI bleed, visceral perforation, major uncontrolled bleeding from laceration or injury)
• Patient receiving initial care by a non-PART participating EMS agency capable of performing ETI, LT, or other advanced airway management
• Patients with ET tube, LT or other advanced airway device inserted prior to participating EMS agency arrival (e.g., inserted by healthcare facility personnel)
• Patients with a pre-existing tracheostomy
• Obvious asphyxial cardiac arrest (e.g., choking, foreign body aspiration, angioedema, epiglottitis, trauma to mouth and face, etc.)
• Patients with a left ventricular assist device (LVAD) or total artificial heart (TAH)
• Patients with pre-existing written "do-not-attempt-resuscitation" (DNAR) orders
• Inter-facility transports
• Patients with a "do not enroll" bracelet

Where it is running

• Alabama Resuscitation Center — Birmingham, Alabama, United States
• Portland Resuscitation Outcomes Consortium, Oregon Health & Sciences University — Portland, Oregon, United States
• The Pittsburgh Resuscitation Network, University of Pittsburgh — Pittsburgh, Pennsylvania, United States
• Dallas Center for Resuscitation Research, University of Texas Southwestern Medical Cente — Dallas, Texas, United States
• University of Washington (Data Coordinating Center) — Seattle, Washington, United States
• Milwaukee Resuscitation Network, Medical College of Wisconsin — Milwaukee, Wisconsin, United States

Full record on ClinicalTrials.gov

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