Early-onset Obesity and Cognitive Impairment in Children With Pseudohypoparathyroidism

Completed

Conditions studied: Pseudohypoparathyroidism, Albright Hereditary Osteodystrophy

In brief

Pseudohypoparathyroidism type 1a (PHP1a) is a rare disease that causes childhood obesity and learning difficulties. This study will investigate eating behaviors and perform cognitive testing on children with PHP1a. The investigators will compare their results to those of healthy siblings and other obese children.

Key facts

Study ID

NCT02411461

Run by

Vanderbilt University Medical Center

People needed

39

Starts

2014-12-01

Expected to finish

2017-01-01

Last updated by the study team

2019-11-13

Who can join

Age: 6 and older, up to 18. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Clinical diagnosis of PHP1a, sibling of a patient with PHP1a or matched obese control
• Exclusion Criteria (PHP1a):
• Treatment with appetite-altering drug or initiation of a new weight loss program in the past 3 months
• Type 2 diabetes
• Exclusion Criteria (Controls):
• Obesity due to a genetic syndrome, growth hormone deficiency, untreated hypothyroidism, Cushing syndrome or exogenous glucocorticoid administration
• Weight loss greater than 10% over the previous 6 months
• Autism or other significant learning disorder
• Type 2 diabetes
• Other significant medical condition

Where it is running

• Vanderbilt University — Nashville, Tennessee, United States

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.