Influence of Lifestyle Factors on Neutrophil Migration Pilot Study

Completed · Not applicable

Conditions studied: Neutrophil Chemotactic Response

In brief

This study will determine how common lifestyle practices affect the behavior of neutrophils (a type of immune cell) at shorter time scales than previously possible.

Key facts

Study ID

NCT02411318

Run by

University of Wisconsin, Madison

People needed

47

Starts

2014-09-25

Expected to finish

2019-12-31

Last updated by the study team

2020-12-17

Who can join

Age: 21 and older, up to 60. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Capacity to provide informed consent and ability to speak and read English.
• Male or female with no chronic or acute health concerns that might affect subject safety during the study or interfere with the study results
• No intake of medication that the researchers believe will significantly influence immune function in the 48 hours proceeding the lancet puncture (examples given in the section entitled "Exclusion Criteria")
• In good physical health
• Regularly exercise at least 30 minutes 3 times per week (exercise cohort)

You may not qualify if…

• Currently participating in another clinical trial
• History of significant systemic disease (eg. cancer, infection, hematological, renal, hepatic, coronary artery disease or other cardiovascular disease, endocrinologic, neurologic, rheumatologic, or gastrointestinal disease)
• Use of beta blockers or corticosteroids
• Currently taking medications that are not recommended to be taken in conjunction with alcohol
• Acute illness or evidence of clinically significant active infection
• Currently receiving immunotherapy
• Pregnant women
• Ingested medication (e.g. systemic corticosteroids) within 48 hours preceding the draw that the researchers believe may have an effect on immune response or the immune system
• Performed any activity that conflicts (eg. drinking any alcohol prior to the study), in the judgment of the investigator, with the external factor to be tested in the study (if any)
• Alcoholic or other health conditions for which alcohol consumption is contraindicated
• Consume more than 7 drinks per week (women alcohol cohort)
• Consume more than 14 drinks per week (men alcohol cohort)
• Consume more than three (8 oz.) servings of coffee, caffeinated soft drinks/tea (12 oz.) per day (caffeine cohort)

Where it is running

• University of Wisconsin — Madison, Wisconsin, United States

Full record on ClinicalTrials.gov

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