Faces: Choices Study

Withdrawn before enrolling · Phase 2/Phase 3 · Has a placebo group

Conditions studied: Socioemotional Aging

In brief

The neuropeptide oxytocin (OXT), originally known for its role in inducing uterine contractions has been shown to be involved in many of the social capacities that seem to change with age, such as emotion detection and identification, enhanced social memory, empathy, and trust. Thus, age-related changes in the OXT system may underlie differences between young and older adults in socioemotional functioning. Research on the effects of oxytocin in aging is very scarce; therefore, the purpose of this research project is to determine the effects of oxytocin on socioemotional aging. The aim of this research is to examine the behavioral and neural effects of OXT on decisions of trust in social interactions, perceptions of facial trustworthiness, the ability to read faces, and levels of empathy with other people in samples of young and older adults.

Key facts

Study ID

NCT02409862

Run by

University of Florida

People needed

0

Starts

2019-01-01

Expected to finish

2019-08-30

Last updated by the study team

2018-11-26

Who can join

Age: 18 and older, up to 85. Sex: male. Healthy volunteers: accepted.

You may qualify if…

• Between the ages of 18-33 (for the younger adults) and 60-85 (for the older adults)
• Male
• Caucasian
• English fluency

You may not qualify if…

• Severe claustrophobia
• Currently on vasoconstrictors, pseudoephedrine or antidiuretic medication
• Surgery on the brain or any prior serious brain damage or disease
• Dementia or severe cognitive disorders
• History of hyponatremia, Syndrome of Inappropriate Antidiuretic Hormone, psychogenic polydipsia, or motion disorder

Where it is running

• University of Florida — Gainesville, Florida, United States

Full record on ClinicalTrials.gov

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