CRIC-Visceral Adiposity and Physical Fitness in Chronic Kidney Disease
Completed
Conditions studied: Renal Insufficiency, Chronic, Obesity
In brief
Obesity and chronic kidney disease (CKD) are major public health problems. In contrary to observations in general population, higher body mass index in those with pre-existing CKD is associated with lower mortality. Chronic Renal Insufficiency Cohort (CRIC) is an ongoing observational study to examine the consequences of CKD with a particular focus on cardiovascular illness like myocardial infarction (heart attack) and stroke. Among CRIC study participants, the investigators propose to obtain visceral and subcutaneous adiposity and physical fitness measures and study its associations with patient-centered outcomes. This study will help the investigators understand the independent and combined effects of visceral adiposity and physical fitness on cardiovascular disease, renal disease progression and death among those with CKD. Further, it will identify mechanisms that could be targeted to reduce the detrimental effects of visceral adiposity in those with kidney disease.
Key facts
- Study ID
- NCT02405650
- Run by
- Baylor College of Medicine
- People needed
- 453
- Starts
- 2015-04-01
- Expected to finish
- 2018-03-31
- Last updated by the study team
- 2019-07-22
Who can join
Age: 21 and older, up to 79. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Age 21-79
- Estimated Glomerular Filtration Rate 20-74 ml/min/1.73m\^2
You may not qualify if…
- Pacemaker
- Metallic prosthesis or foreign body (joints, heart valves, clips)
- Sites may include patients with cardiac stents and/or dental implants based on the local Radiology department criteria i.e. if there are no restrictions, they can include patients with stents and/or dental implants. If the Radiology department mandates the type of stent details and/or dental implants, site coordinator should provide this to the local Radiology department and obtain permission before enrolling the subject.
- Severe claustrophobia
- Severe osteoarthritis (use of walker or other assisted devices)
- Sites may include patients with cane (single or quad).
- Recent cardiovascular or cerebrovascular events (within 6 months prior to enrollment)
- Kidney transplant
- Currently on dialysis
- Peripheral vascular disease limiting long distance walking
Where it is running
- University of Illinois at Chicago — Chicago, Illinois, United States
- University of Maryland Medical System — Baltimore, Maryland, United States
- Johns Hopkins University - ProHealth — Baltimore, Maryland, United States
- University of Michigan — Ann Arbor, Michigan, United States
- Case Western Reserve University — Cleveland, Ohio, United States
- Metro Health Medical Center — Cleveland, Ohio, United States
- Cleveland Clinic — Cleveland, Ohio, United States
- University of Pennsylvania Scientific & Data Coordinating Center — Philadelphia, Pennsylvania, United States
- University of Pennsylvania — Philadelphia, Pennsylvania, United States
- Baylor College of Medicine — Houston, Texas, United States
Full record on ClinicalTrials.gov
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