IV Acetaminophen for Postoperative Pain Analgesia After Laparoscopic Hysterectomy
Completed · Phase 4 · Has a placebo group
Conditions studied: Pain
In brief
The objective of this study is to quantify the change in post-operative pain scores and narcotic requirements in women receiving pre and post-operative IV acetaminophen compared to placebo in women undergoing laparoscopic hysterectomy.
Key facts
- Study ID
- NCT02400580
- Run by
- University of Pittsburgh
- People needed
- 183
- Starts
- 2015-02-01
- Expected to finish
- 2016-09-01
- Last updated by the study team
- 2018-06-13
Who can join
Age: 18 and older, up to 75. Sex: female. Healthy volunteers: accepted.
You may qualify if…
- Women aged 18-75
- Ability to read and write in English (our post-operative pain log is only available in English)
- Planning a laparoscopic hysterectomy (includes total laparoscopic hysterectomy, laparoscopic supracervical hysterectomy, laparoscopically assisted vaginal hysterectomy, with or without salpingooophorectomy)
You may not qualify if…
- Answering yes to any of the following questions: "Do you have a history of liver disease, kidney disease, hepatitis C, history of liver failure, greater than 3 drinks per day or being have you ever been told by your doctor that they should not take acetaminophen"
- History of cardiac arrhythmia
- History of jaundice
- Acute abdominal inflammatory or infectious process at time of surgery
- Known malignancy at time of surgery
- Known pregnancy at time of surgery
- Plan to perform additional significant surgical procedure at the time of hysterectomy such as extensive excision of endometriosis on bowel or bladder or pelvic reconstructive procedure
- >6cm abdominal incision in order to remove the uterus at time of study-related hysterectomy
- Regular use of narcotic pain medication (defined as use on most days of the week at any point in the past 3 months)
- Allergy to acetaminophen
- Women who weigh less than 50 kilograms on the day of surgery.
Where it is running
- Magee Womens Hospital — Pittsburgh, Pennsylvania, United States
Full record on ClinicalTrials.gov
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