Oral Alkali Production and Caries Prevention in Children (Longitudinal)

Completed

Conditions studied: Dental Caries

In brief

The fact that dental caries remains a major public health problem mandates that oral-health researchers explore new strategies for assessment of caries risk, as well as for caries prevention and management. Dental caries occurs when acids produced by bacterial glycolysis of dietary carbohydrates causes demineralization of the tooth enamel. A major focus of caries research has been on identifying and characterizing acid-generating bacteria and the mechanisms of acid resistance. The purpose of this study is to investigate over time the relationship between alkali production and caries.

Key facts

Study ID

NCT02398695

Run by

University of Florida

People needed

232

Starts

2012-10-01

Expected to finish

2015-08-27

Last updated by the study team

2018-11-13

Who can join

Age: 2 and older, up to 7. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Age 2 to 7 years

You may not qualify if…

• Treated with antibiotics within the past 3 months
• taking any medication at the time of the study
• uses orthodontic appliance, and
• has performed oral hygiene procedures in the past 8 hour prior to the collection appointment.

Where it is running

• Dental Clinical Research Unit, University of Florida — Gainesville, Florida, United States

Full record on ClinicalTrials.gov

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