Study to Investigate Adipocyte Cell and Lipid Turnover in Obese Adolescents

Completed

Conditions studied: Pediatric Obesity

In brief

Insulin Resistance is the best predictor of whether the obese adolescent will develop type 2 diabetes. The present studies will focus on determining what might cause fat to accumulate in the subcutaneous fat regions and lead to local inflammation, causing insulin resistance to develop in obese adolescents.

Key facts

Study ID

NCT02395003

Run by

Yale University

People needed

26

Starts

2016-04-01

Expected to finish

2023-03-07

Last updated by the study team

2024-02-26

Who can join

Age: 12 and older, up to 18. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Overweight (85-95th% age and gender specific) or Obese (>95th% age and gender specific)
• Ages 12-18 years
• Absence of any endocrinopathy
• Absence of any therapy with medication known to alter glucose metabolism (i.e.: Oral steroids, certain psychiatric medications such as Xeleca, Lithium, Paxil)
• English Speaking subjects

You may not qualify if…

• Any disease known to alter glucose metabolism (T2DM)
• Diuretic Medication
• Pregnant or breastfeeding
• Type 1 or 2 diabetes

Where it is running

• Yale — New Haven, Connecticut, United States

Full record on ClinicalTrials.gov

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