Efficacy of Novel Drug-combinations for Relief of Psoriasis

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Conditions studied: Psoriasis

In brief

ENDURE is a prospective, observational study aimed to document clinical response and side effects associated with compounded psoriasis medications when prescribed as routine care. As a secondary initiative, this study will assess methotrexate systemic absorption and toxicity in patients prescribed a methotrexate-containing compounded formulation.

Key facts

Study ID

NCT02394301

Run by

Medimix Specialty Pharmacy, LLC

People needed

200

Starts

2015-02-01

Expected to finish

2015-12-01

Last updated by the study team

2015-05-18

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• >18 years of age
• Diagnosis of psoriasis vulgaris
• Being initiated on a topical compounded medication for psoriasis from Medimix Specialty Pharmacy containing at least 3 of the following ingredients as part of standard of care: corticosteroid, methotrexate, retinoic acid, vitamin D3 or synthetic analog, urea, AND/OR a shampoo/spray containing a corticosteroid and vitamin D3 or synthetic analog for the first time.

You may not qualify if…

• Pregnancy \& nursing
• Active infectious disease
• Kidney abnormalities
• Blood deficiencies
• Alcohol consumption
• Immunodeficiency syndromes
• History of systemic psoriasis medications, including conventional DMARDs, oral retinoids, oral calcineurin inhibitors, TNF-inhibitors, and monoclonal antibodies within the past 120 days
• Current or planned use of concomitant psoriasis medications and/or phototherapy
• Any additional health conditions or concomitant use of other prescription/over-the-counter products that may confound the study results at the discretion of the study investigators

Where it is running

• The Medimix Specialty Pharmacy, LLC — Jacksonville, Florida, United States

Full record on ClinicalTrials.gov

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