theFRESHstudy: FRequency of Eating and Its Influence on Satiety and Health

Completed · Not applicable

Conditions studied: Healthy

In brief

Eating frequency may play an independent role in appetite regulation, overall caloric consumption and measures of long-term health or disease risk. Some literature recommends frequent eating, but pilot data suggest that this type of eating pattern may be harmful to health since it leaves the body in a perpetual fed state and increases systemic inflammation. Therefore, the investigators will conduct a clinical trial in 50 healthy adults to compare a low frequency eating pattern to a high frequency eating pattern in relation to blood-based markers of inflammation, metabolic health and appetite. Study results will be applied to recommendations for eating frequency in the context of an overall healthy diet.

Key facts

Study ID

NCT02392897

Run by

Fred Hutchinson Cancer Center

People needed

50

Starts

2015-04-01

Expected to finish

2018-12-19

Last updated by the study team

2019-07-25

Who can join

Age: 18 and older, up to 50. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Normal, overweight and obese males and females
• BMI = 18.5-24.9 and 28.0-40.0 kg/m²
• Ages 18-50 years
• Live in Seattle, WA

You may not qualify if…

• Pregnant women
• Presence of diseases requiring dietary modification, including physician diagnosed cardiovascular disease or diabetes mellitus, use of medications that may impact study results including non-steroidal anti-inflammatory drugs (NSAIDS)
• Abnormal fasting glucose (>100 mg/dL)
• History of disordered or restrained eating and severe food restrictions
• Individuals with BMI ≥ 40 kg/m2

Where it is running

• Fred Hutchinson Cancer Research Center — Seattle, Washington, United States

Full record on ClinicalTrials.gov

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