A Novel Neurorehabilitation Approach for Cognitive Aging With HIV

Completed · Not applicable · Has a placebo group

Conditions studied: HIV, Aging

In brief

The goal of this study is to conduct a small, self-contained project to test the hypothesis that tDCS will augment SOP cognitive remediation therapy (CRT) in older HIV+ adults. The investigators will randomly assign 60 HIV+ older adults (i.e., ≥ 50 years old) to 10-hours in either a SOP CRT + sham tDCS condition (n=30) or SOP CRT + active tDCS condition (n=30) and examine neurocognitive functioning at baseline and 6 weeks post-intervention. Hypothesis 1: The SOP CRT + active tDCS condition will show larger proximal (i.e., SOP) gains than the SOP CRT + sham tDCS condition. Hypothesis 2: The active tDCS condition will demonstrate generalization to secondary neurocognitive domains compared to the sham tDCS condition.

Key facts

Study ID

NCT02391311

Run by

University of Alabama at Birmingham

People needed

42

Starts

2015-03-01

Expected to finish

2016-01-01

Last updated by the study team

2017-05-15

Who can join

Age: 50 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• HIV+
• Aged 50 and older
• Patient at University HIV/AIDS Clinic

You may not qualify if…

• Not homeless
• Not blind or deaf
• No significant neuromedical issues (e.g., schizophrenia, bipolar disorder, stroke, epilepsy or history of seizures)
• No pacemaker or other biomedical devices or metal implants
• No untreated hypertension
• Not undergoing chemo or radiation
• No head injury with LOC greater than 30 mins

Where it is running

• UAB 1917 Clinic — Birmingham, Alabama, United States

Full record on ClinicalTrials.gov

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