Use of Rotational Thromboelastometry (ROTEM) to Characterize Coagulation Abnormalities in Burn Patients

Stopped early · Not applicable

Conditions studied: Burn

In brief

This is an interventional pilot study of 40 burn inpatients. Specific aims of the proposed pilot study are to use bedside blood analysis with rotational thromboelastometry (ROTEM) in severe burn patients to provide preliminary information on the nature of coagulation abnormalities and compare subject ROTEM coagulation profiles within 24 hours of burn injury (day 1) and on days 2, 3, 5, 7, 14 and 21 after burn injury.

Key facts

Study ID

NCT02388776

Run by

Weill Medical College of Cornell University

People needed

2

Starts

2015-01-01

Expected to finish

2016-06-01

Last updated by the study team

2018-07-05

Who can join

Age: 3 and older, up to 100. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Consecutive patients admitted to NYPH with 15% TBSA burn or greater.
• Patients with vascular access catheters (arterial or central line) placed within 24 hours of burn injury
• Males and females
• Ages >3 years or >15 kg
• Informed verbal consent obtained from the patient or the patient's designated health care proxy (DHCP). In the case of minors, assent and informed verbal consent obtained from at least one parent or guardian.

You may not qualify if…

• Known pre-existing hemostatic abnormalities
• Ages < 3 years or weight < 15 kg
• Intake of anticoagulants or antiplatelet aggregation inhibitors prior to burn
• Pregnant patients
• Patients with delayed presentation (greater than 24 hours after burn injury)
• Inclusion in another clinical research study
• Refusal or inability of patient or patient's DHCP to consent in English.

Where it is running

• Weill Cornell Medical College — New York, New York, United States

Full record on ClinicalTrials.gov

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