Magnetic Resonance Elastography in Patients With Abdominal Aortic Aneurysms

Recruiting now

Conditions studied: Abdominal Aortic Aneurysm

In brief

The main objective of this study is to utilize Magnetic Resonance Elastography (MRE) to determine tissue stiffness of abdominal aortic aneurysms (AAA). For patients with AAA, MRE is a more sensitive and superior method of determining the risk for rupture of AAA based on stiffness estimates when compared to the current, crude method of assessing risk based on measurement of the diameter of the aneurysm. The investigators will also validate the stiffness estimates against gold standard i.e. mechanical testing and histopathology only AAA patients undergoing AAA surgery.

Key facts

Study ID

NCT02387255

Run by

Ohio State University

People needed

165

Starts

2014-10-01

Expected to finish

2028-10-31

Last updated by the study team

2025-04-08

Who can join

Age: 20 and older. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Must be able to lie flat on their back in the scanner for up to 60 minutes
• Must be able to hold breath for up to 15 seconds

You may not qualify if…

• Patients who are claustrophobic
• Patients who are pregnant
• Patients with any unapproved, non-MRI save metal/devices in or on their body

Where it is running

• The Ohio State University Medical Center — Columbus, Ohio, United States (enrolling)

Full record on ClinicalTrials.gov

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