Multicenter Trial Evaluating Quality of Tears Produced by Nasal Neurostimulation

Completed · Not applicable

Conditions studied: Dry Eye Syndromes

In brief

The objectives of this study are: * To compare the change in levels of tear proteins and inflammatory mediators pre and post administration between the intranasal and extranasal applications * To compare the goblet cell count following application between the intranasal and extranasal applications * To compare fluorescein tear clearance with the application of the device intranasally and extranasally applications

Key facts

Study ID

NCT02385292

Run by

Oculeve, Inc.

People needed

23

Starts

2015-05-31

Expected to finish

2016-03-31

Last updated by the study team

2021-10-19

Who can join

Age: 22 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Bilateral dry eyes
• Capable of providing written informed consent

You may not qualify if…

• Chronic or recurring epistaxis (nosebleeds)
• Blood coagulation disorder
• Uncontrolled or poorly controlled diabetes
• Heart or pulmonary disease
• Females who are pregnant, planning a pregnancy or nursing

Where it is running

• Grutzmacher, Lewis & Sierra — Sacramento, California, United States
• Baylor College of Medicine, Department of Ophthalmology — Houston, Texas, United States

Full record on ClinicalTrials.gov

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