Effect of Childhood Radioiodine Therapy on Salivary Function

Completed

Conditions studied: Xerostomia, Hyperthyroidism, Thyroid Cancer

In brief

Radioiodine (I-131) therapy for thyroid disease is known to decrease salivary function in adult patients. The impact of pediatric I-131 exposure on salivary function is unknown. The investigators goals are to answer this question by measuring salivary gland function before and after I-131 administration in children who receive radioiodine therapy at our hospital for thyroid disease.

Key facts

Study ID

NCT02375451

Run by

Boston Children's Hospital

People needed

70

Starts

2014-09-01

Expected to finish

2016-09-01

Last updated by the study team

2017-06-26

Who can join

Age: 3 and older, up to 55. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Patients who have been treated with radioiodine therapy
• Patients who have never received radioiodine therapy (negative control group)

You may not qualify if…

• Non-English speaking subjects will be excluded due to our lack of translation support resources at this time. Of note, participation in our study cannot benefit participants in any way.

Where it is running

• Boston Children's Hospital — Boston, Massachusetts, United States

Full record on ClinicalTrials.gov

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