Accurate Test of Limb Isometric Strength (ATLIS) in ALS
Status unconfirmed
Conditions studied: Amyotrophic Lateral Sclerosis
In brief
A strength measurement device called Accurate Test of Limb Isometric Strength (ATLIS) was developed to precisely and conveniently measure static limb strength in patients with ALS. The investigator will compare ATLIS data with data from the commonly used ALS outcomes measure, the ALS Functional Rating Scale-Revised (ALSFRS-R), as well as an exploratory measure, electrical impedance myography (EIM), in a prospective, longitudinal study. Both outcomes measures will be performed on 100 subjects collected preferably at bi-monthly clinic visits during the study period.
Key facts
- Study ID
- NCT02374606
- Run by
- Cedars-Sinai Medical Center
- People needed
- 100
- Starts
- 2015-03-01
- Expected to finish
- 2020-02-01
- Last updated by the study team
- 2018-04-03
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Subjects 18 years or older diagnosed with clinically possible, laboratory supported probable, probable or clinically definite ALS according to the World Federation of Neurology Revised El Escorial Criteria.
- Capable of providing informed consent and complying with trial procedures.
- Active movement of at least two limbs at the time of study entry
- Intend to routinely attend clinic for neurological care at the clinical site
You may not qualify if…
- Patients, judged by the site clinical investigator to have medical conditions that may limit their ability to safely exert maximal force using the muscles in their arms and legs will be excluded from this study (e.g. unstable hypertension, significant cardiac disease, significant musculoskeletal disorders, or other medical conditions).
- Patients judged by the site clinical investigator to have significant clinical evidence of unstable medical or psychiatric illness will be excluded.
Where it is running
- Cedars-Sinai Medical Center — Los Angeles, California, United States (enrolling)
Full record on ClinicalTrials.gov
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