Asthma in the Elderly: A Study of Choline Supplementation

Completed · Phase 3 · Has a placebo group

Conditions studied: Asthma in the Elderly

In brief

Asthma in the elderly is poorly understood, as most studies have not included this patient group. In a previous study of adults with asthma, choline supplementation had a positive effect on asthma symptoms and allowed to decrease asthma pharmacologic treatment. The present study is a randomized, double-blind, placebo-controlled, cross-over study of choline supplementation. The investigators will study the effect of choline 650 mg taken orally twice daily x 6 weeks versus placebo on asthma symptom scores (Asthma Control Test) and spirometric values (FEV1, FEV1/FVC, FEF25-75%). The investigators will also look at the effect of choline supplementation on peripheral blood eosinophils, serum immunoglobulin E (IgE) and homocysteine levels.

Key facts

Study ID

NCT02371993

Run by

Rohr and Columbo Asthma, Allergy and Immunology Specialists, P.C.

People needed

30

Starts

2015-01-01

Expected to finish

2015-06-01

Last updated by the study team

2015-10-29

Who can join

Age: 65 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Asthma

You may not qualify if…

• No history of smoking more than 10 pack/years,
• no gastrointestinal cancers,
• no liver or kidney disease,
• no bipolar disorder.

Where it is running

• Rohr and Columbo Asthma, Allergy and Immunology Specialists, P.C. — Bryn Mawr, Pennsylvania, United States

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.