Study of MEDI4736 Monotherapy and in Combination With Tremelimumab Versus Standard of Care Therapy in Patients With Head and Neck Cancer
Completed · Phase 3
Conditions studied: Recurrent or Metastatic PD-L1-positive or -Negative Squamous Cell Carcinoma of the Head and Neck SCCHN
In brief
This is a randomized, open-label, multi-center, global, Phase III study to determine the efficacy and safety of MEDI4736 + tremelimumab combination therapy and MEDI4736 monotherapy versus SoC therapy in the target patient population.
Key facts
- Study ID
- NCT02369874
- Run by
- AstraZeneca
- People needed
- 736
- Starts
- 2015-09-09
- Expected to finish
- 2020-11-13
- Last updated by the study team
- 2021-02-10
Who can join
Age: 18 and older, up to 96. Sex: any. Healthy volunteers: not accepted.
Where it is running
- Research Site — Fullerton, California, United States
- Research Site — Los Angeles, California, United States
- Research Site — Redondo Beach, California, United States
- Research Site — Stanford, California, United States
- Research Site — Denver, Colorado, United States
- Research Site — Newark, Delaware, United States
- Research Site — Miami Beach, Florida, United States
- Research Site — Orlando, Florida, United States
- Research Site — Atlanta, Georgia, United States
- Research Site — Evanston, Illinois, United States
- Research Site — Lexington, Kentucky, United States
- Research Site — Boston, Massachusetts, United States
- Research Site — Rochester, New York, United States
- Research Site — Rochester, New York, United States
- Research Site — Winston-Salem, North Carolina, United States
- Research Site — Pittsburgh, Pennsylvania, United States
- Research Site — Germantown, Tennessee, United States
- Research Site — Nashville, Tennessee, United States
- Research Site — Dallas, Texas, United States
- Research Site — Dallas, Texas, United States
- Research Site — McAllen, Texas, United States
- Research Site — Norfolk, Virginia, United States
- Research Site — CABA, Argentina
- Research Site — San Miguel de Tucumán, Argentina
- Research Site — Tucson, Arizona, United States
Full record on ClinicalTrials.gov
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