Does the Addition of Epinephrine Prolong the Duration of Spinal Anesthesia for Repeat Cesarean Section?

Completed · Phase 4

Conditions studied: Spinal Anesthesia, Cesarean Section

In brief

The purpose of this study is to investigate whether the addition of a medication called epinephrine to spinal medications prolongs the duration of the anesthesia. The medication standardly used in spinal anesthesia is a local anesthetic (bupivacaine) and an opiate pain medication (morphine). These medications typically last about 2 hours. The investigators want to determine if adding epinephrine to the spinal medications prolongs the anesthetic without side effects. A longer duration of anesthesia may be useful in prolonged repeat cesarean section. Epinephrine is known to prolong the action of some local anesthetics, but the investigators want to specifically study combining it with the medications the investigators use regularly for cesarean section. You may qualify to take part in this research study because you are having a repeat cesarean section. Repeat cesarean sections sometimes last longer than 2 hours. The investigators want to determine if epinephrine will prolong the anesthetic.

Key facts

Study ID

NCT02369510

Run by

Icahn School of Medicine at Mount Sinai

People needed

68

Starts

2015-02-01

Expected to finish

2016-05-01

Last updated by the study team

2017-08-30

Who can join

Age: 18 and older, up to 50. Sex: female. Healthy volunteers: accepted.

You may qualify if…

• Non-emergent repeat cesarean section
• Neuraxial anesthesia as the planned primary anesthetic
• Informed consent obtained
• Females age 18-50

You may not qualify if…

• Emergency cesarean section
• Anesthetic other than neuraxial
• Allergy to local anesthetics, morphine, or epinephrine
• Pre-existing sensory/motor deficit

Where it is running

• Icahn School of Medicine at Mount Sinai — New York, New York, United States

Full record on ClinicalTrials.gov

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