Pharmacoeconomics and Related Patient Outcomes of Multi-dose Intravenous Acetaminophen (OFIRMEV)

Completed · Phase 4 · Has a placebo group

Conditions studied: Prostatectomy, Pain

In brief

To examine pharmacoeconomics of IV acetaminophen (Ofirmev). Specifically, to examine its potential to improve hospital efficiency and patient outcomes. The investigators compare the addition of IV acetaminophen versus placebo on postoperative anesthesia care unit recovery times, inpatient hospital length of stay (LOS), postoperative pain scores, consumption of opiates as rescue agents and side effects among patients undergoing robotic-assisted laparoscopic prostatectomy (RALP).

Key facts

Study ID

NCT02369211

Run by

Brigham and Women's Hospital

People needed

86

Starts

2015-09-01

Expected to finish

2018-03-01

Last updated by the study team

2019-09-11

Who can join

Age: 18 and older, up to 85. Sex: male. Healthy volunteers: accepted.

You may qualify if…

• Patients undergoing robotic-assisted laparoscopic prostatectomy
• ≥18 years old males
• American Society of Anesthesiologists class 1-4

You may not qualify if…

• Chronic opiate use
• Liver disease (known history of hepatitis B or C, cirrhosis, nonalcoholic steatohepatitis, history of alcoholism, liver function test results greater than 3 times upper limit of normal in the past 3 months)
• Allergy/hypersensitivity to acetaminophen
• Patients with baseline dementia
• Chronic diathesis
• Chronic kidney disease

Where it is running

• Brigham and Women's Hospital — Boston, Massachusetts, United States

Full record on ClinicalTrials.gov

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