A Study to Evaluate the Effect of Increased Stomach pH on Evacetrapib in Healthy Participants

Completed · Phase 1

Conditions studied: Healthy

In brief

The purpose of this study is to evaluate the effect of increased stomach pH on how much evacetrapib is found in the blood stream and how long the body takes to get rid of it when given to healthy participants. Information about any side effects that may occur will also be collected. There are two parts to the study. Participation in both parts will be required. The study will last approximately 30 days, not including screening.

Key facts

Study ID

NCT02365558

Run by

Eli Lilly and Company

People needed

34

Starts

2015-01-01

Expected to finish

2015-04-01

Last updated by the study team

2018-10-03

Who can join

Age: 18 and older, up to 65. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Overtly healthy participants, as determined by medical history and physical examination
• Females must be of non-child-bearing potential
• Have a body mass index of 18 to 32 kilograms per square meter (kg/m\^2)

You may not qualify if…

• Have known allergies to evacetrapib, omeprazole, related compounds, or any components of the evacetrapib or omeprazole formulations

Where it is running

• Covance Madison — Madison, Wisconsin, United States

Full record on ClinicalTrials.gov

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