Cardioprotective Activities Of Whole Eggs On Vascular Endothelial Function In Prediabetic Adults
Completed · Not applicable
Conditions studied: Prediabetes, Cardiovascular Disease
In brief
Cardiovascular disease (CVD) is largely a lifestyle-related condition that is the #1 killer of adults in the United States. Our work is aimed at understanding how short-term increases in blood sugar, like those that accompany eating a meal, affect blood vessel function and the risk of CVD. This research is aimed at understanding how meals composed of eggs affect short-term increases in blood sugar from eating, which are connected with increased risk of CVD. In particular, the investigators are trying to identify a specific meal composed of either whole eggs, egg yolks, or egg whites, that best reduces acute increases in blood sugar brought on by meals that consist of majority carbohydrate. At the same time, the investigators are trying to explore the protective affects that eggs may have on blood vessel function and the reduction of CVD risk.
Key facts
- Study ID
- NCT02364570
- Run by
- Ohio State University
- People needed
- 20
- Starts
- 2015-01-01
- Expected to finish
- 2017-06-01
- Last updated by the study team
- 2019-05-03
Who can join
Age: 18 and older, up to 50. Sex: male. Healthy volunteers: accepted.
You may qualify if…
- fasting glucose 100-125 mg/dL,
- non-dietary supplement user,
- no medications affecting vasodilation, inflammation, or energy metabolism,
- no CVD,
- nonsmokers,
- individuals having blood pressure <130/85 mmHg and total cholesterol <240 mg/dL.
You may not qualify if…
- unstable weight (±2 kg),
- vegetarian or egg allergy,
- alcohol intake >3 drinks/d or >10 drinks/wk), or
- ≥7 h/wk of aerobic activity.
Where it is running
- The Ohio State University — Columbus, Ohio, United States
Full record on ClinicalTrials.gov
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