Ketamine: Comparison of IV Push vs. IV Drip

Completed · Not applicable

Conditions studied: Pain

In brief

Our previous published research comparing the efficacy of intravenous ketamine to morphine has shown ketamine to provide equivalent relief of moderate to severe acute pain in emergency medicine patients. Secondary analysis of the previous published research has also revealed ketamine to have statistically more side effects. The investigators believe that increasing the time of administration of the ketamine, from a push injection to a drip infusion, will minimize the side effects experienced by recipients of ketamine.

Key facts

Study ID: NCT02363270
Run by: Antonios Likourezos
People needed: 48
Starts: 2015-04-01
Expected to finish: 2017-02-28
Last updated by the study team: 2017-11-22

Who can join

Age: 18 and older, up to 65. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

Emergency Medicine patients
Adult patients (18-65 years of age)
Moderate to severe pain (Numeric Pain Rating Score =5).
Patients must be awake, alert and oriented to time, place and person.
Patients must be able to demonstrate understanding of the informed consent, and also able to verbalize how much pain they are having on the 10 point Numeric Rating Pain Scale, and the nature of the side effects they may be experiencing from the IV analgesia

You may not qualify if…

Patients with cognitive deficits that are not able to demonstrate understanding as described above.
Patient's reported weight of less than 45kg or more than 115kg.
Patients with altered mental status, alcohol intoxication, eye trauma.
Patients with hemodynamic instability (Systolic Blood pressure <90), and malignant hypertension.
allergy to ketamine
Pregnancy or breast feeding.

Where it is running

Maimonides Medical Center — Brooklyn, New York, United States

Full record on ClinicalTrials.gov

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