Diet and Exercise in Pompe Disease

Completed · Not applicable

Conditions studied: Pompe Disease, Glycogen Storage Disease Type II, Lysosomal Storage Diseases

In brief

This study examines the effects of individualized diet and exercise plans on muscle strength, quality of life and respiratory function in Pompe disease. Subjects will be given a diet and exercise plan based on their individual needs, which will be followed for 16 weeks. Participants will also be provided with an activity tracker in order to track their exercise activities, access to an app that will allow them to input their daily food intake, and they will also come to the University of Florida for exercise tests, respiratory tests and questionnaires.

Key facts

Study ID

NCT02363153

Run by

University of Florida

People needed

2

Starts

2017-11-06

Expected to finish

2021-05-12

Last updated by the study team

2021-05-14

Who can join

Age: 15 and older, up to 55. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Male or female subjects 15-55 years of age;
• Have a diagnosis of Pompe disease, as defined by protein assay and/or DNA sequence of the acid alpha-glucosidase gene, with present clinical symptoms of the disease;
• Be naïve to ERT or receiving ERT for at least eighteen months prior to beginning study;
• Be able to walk at least 40m in the 6 minute walk test.
• Willing to comply with study requirements

You may not qualify if…

• Be pregnant;
• Be in the lower limit for pulmonary function; FVC < 30% predicted;
• Be dependent on assisted ventilation;
• Be dependent on wheelchair;
• Have evidence of clinical heart failure;
• Have any contraindication to exercise

Where it is running

• University of Florida Clinical Research Center — Gainesville, Florida, United States

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.