Human Lycopene and Beta-cryptoxanthin Absorption From Citrus Fruit

Completed · Not applicable

Conditions studied: Bioavailability of Carotenoids

In brief

The goal of the research study is to measure and compare the absorption of equivalent amounts of beta-cryptoxanthin and Iycopene provided in citrus fruit. The investigators want to determine whether adults absorb beta-cryptoxanthin to a greater extent than lycopene, when both are supplied in comparable citrus fruits.

Key facts

Study ID

NCT02348164

Run by

USDA, Western Human Nutrition Research Center

People needed

23

Starts

2007-12-01

Expected to finish

2009-02-01

Last updated by the study team

2015-01-28

Who can join

Age: 18 and older, up to 65. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Non-smoking
• Body mass indexes between 18 and 35
• Blood pressure under 150/90 mm Hg
• Not pregnant, lactating, or planning a pregnancy within 90 days.

You may not qualify if…

• Total cholesterol concentrations over 250 mg/dL
• Total fasting triacylglycerol concentrations over 175 mg/dL.
• Taking lipid-lowering medications (gemfibrozil, niacin, lovastatin, simvastatin)
• Taking fat blocking medications (such as orlistat)
• Taking medicines containing high dosages of retinoids such as Accutane
• Taking carotenoid dietary supplements
• Known allergy to tangerines or pink grapefruit
• Consuming more than 2 alcoholic drinks per day

Where it is running

• USDA, ARS, Western Human Nutrition Research Center — Davis, California, United States

Full record on ClinicalTrials.gov

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