Chest Pain Perception and Capsaicin Sensitivity in Patients With Acute Cardiac Ischemia

Completed · Not applicable

Conditions studied: Chest Pain

In brief

The purpose of this study is to determine whether there is a positive correlation between the ability to sense chest pain in the context of myocardial ischemia and the ability to sense discomfort associated with the topical application of the TRPV1 agonist capsaicin (the active ingredient on hot chili peppers).

Key facts

Study ID

NCT02346916

Run by

Bassett Healthcare

People needed

22

Starts

2013-10-01

Expected to finish

2015-08-01

Last updated by the study team

2021-03-04

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Subjects will consist of patients who have undergone clinically-indicated PCI for the treatment of coronary artery disease. This study will include clinically unstable patients, such as those undergoing emergency percutaneous coronary intervention (PCI) for acute myocardial infarction, etc.

You may not qualify if…

• Patients with documented hypersensitivity to capsaicin will be excluded and patients who have used a capsaicin-based product within the last 3 months will be excluded

Where it is running

• Bassett Healthcare Network — Cooperstown, New York, United States

Full record on ClinicalTrials.gov

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