Cognitive Dysfunction in Parkinson's Disease

Completed · Not applicable · Has a placebo group

Conditions studied: Parkinson's Disease

In brief

This study plans to learn more about the brain function related to thinking problems in individuals with Parkinson's disease.

Key facts

Study ID

NCT02346708

Run by

University of Colorado, Denver

People needed

49

Starts

2014-01-01

Expected to finish

2020-12-01

Last updated by the study team

2021-02-09

Who can join

Age: 40 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Diagnosis of probable PD (using United Kingdom Brain Bank criteria)
• Diagnosis of mild cognitive impairment
• No unstable medical condition

You may not qualify if…

• Features suggestive of other causes of Parkinsonism or other neurological disorders
• Prior deep brain stimulation (DBS) or ablation surgery
• Evidence for active depression or Hospital Anxiety and Depression Scale (HADS) score greater than or equal to 11
• Motor symptoms expected to interfere with scanning (e.g. sever tremor)
• Contraindications to TMS, MEG, or MRI such as pregnancy, pacemaker, unstable cardiac disease, skull lesion, claustrophobia, history of epilepsy, or on medications known to lower seizure threshold
• Implanted electronic devices or metal

Where it is running

• University of Colorado School of Medicine — Aurora, Colorado, United States

Full record on ClinicalTrials.gov

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