Phase 2/3, Randomized, Double-Masked, Sham-Controlled Trial of QPI-1007 in Subjects With Acute Nonarteritic Anterior Ischemic Optic Neuropathy (NAION)
Stopped early · Phase 2/Phase 3 · Has a placebo group
Conditions studied: Non Arteritic Anterior Ischemic Optic Neuropathy
In brief
This study will determine the effect of QPI-1007 on visual function in subjects with recent-onset NAION and assess the safety and tolerability of intravitreal injections of QPI-1007 in this population. This study will also evaluate the structural changes in the retina following administration of QPI-1007.
Key facts
- Study ID
- NCT02341560
- Run by
- Quark Pharmaceuticals
- People needed
- 732
- Starts
- 2016-02-24
- Expected to finish
- 2019-07-01
- Last updated by the study team
- 2020-07-20
Who can join
Age: 50 and older, up to 80. Sex: any. Healthy volunteers: not accepted.
Where it is running
- Loma Linda University Eye Institute — Loma Linda, California, United States
- University of Southern California — Los Angeles, California, United States
- NeuroEyeOrbit Institute — Los Angeles, California, United States
- Stanford University — Palo Alto, California, United States
- Unversity of California, Los Angeles (UCLA) — Pasadena, California, United States
- University of Colorado Denver, Department of Neurology — Aurora, Colorado, United States
- Retina Consultants of Southern Colorado, PC — Colorado Springs, Colorado, United States
- The Eye Care Group — Waterbury, Connecticut, United States
- Cape Coral Eye Center — Cape Coral, Florida, United States
- University of Miami Miller School of Medicine/Bascom Palmer Eye Institute — Miami, Florida, United States
- Sarasota Retina Institute — Sarasota, Florida, United States
- Northwestern University — Chicago, Illinois, United States
- University of Illinois at Chicago, Department of Ophthalmology (MC 648) — Chicago, Illinois, United States
- NorthShore University Healthsystem — Glenview, Illinois, United States
- University of Kentucky, Department of Neurology — Lexington, Kentucky, United States
- Greater Baltimore Medical Center — Baltimore, Maryland, United States
- Bethesda Neurology, LLC — Bethesda, Maryland, United States
- Massachusetts Eye and Ear Infirmary — Boston, Massachusetts, United States
- Boston Medical Center — Boston, Massachusetts, United States
- University of Michigan — Ann Arbor, Michigan, United States
- University of Minnesota — Minneapolis, Minnesota, United States
- Mayo Clinic — Rochester, Minnesota, United States
- Washington University in St. Louis — St Louis, Missouri, United States
- University of Nebraska Medical Center and Truhlsen Eye Institute — Omaha, Nebraska, United States
- University of Arkansas Medical Center, Jones Eye Institute — Little Rock, Arkansas, United States
Full record on ClinicalTrials.gov
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