Effect of All-Stim 2 Quadriceps Treatments on Limb Muscle Strength In Mechanically Ventilated Patients
Stopped early · Not applicable · Has a placebo group
Conditions studied: Weakness
In brief
Patients that are on mechanical ventilators in medical intensive care units (MICU) have extremely weak leg muscles. Currently there is no treatment to prevent or reverse this weakness. Treatments with a thigh muscle stimulator, called an All Stim 2, can improve leg muscle strength and help patients regain leg function after knee surgery. The purpose of the present study is to determine if treatments with the All Stim 2 device can also improve leg muscle strength in patients on mechanical ventilation.
Key facts
- Study ID
- NCT02332187
- Run by
- Gerald Supinski
- People needed
- 15
- Starts
- 2013-01-03
- Expected to finish
- 2017-05-05
- Last updated by the study team
- 2022-03-02
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Adult patients requiring mechanical ventilation for more than 48 hours
- Respiratory failure present
You may not qualify if…
- The physician caring for the patient determines that the patient is too unstable
- Use of high dose pressors (more than 15 mcg/min of norepinephrine or more than 15 mg/kg/min of dopamine)
- Use of more than 80% FiO2 (fractional concentration of oxygen) or more than 15 cm H2O (water) of PEEP (positive end expiratory pressure)
- Presence of a cardiac pacemaker or implanted defibrillator
- Use of neuromuscular blocking agents within the 48 hours preceding testing
- History of a preexisting neuromuscular disease
- Presence of profound and uncorrectable hypokalemia (less than 2.5) or hypophosphatemia (less than 1.0)
- Pregnancy
- If the patient is a prisoner
- If the patient is institutionalized
- If it is thought that the patient will have care withdrawn within 7 days
Where it is running
- Chandler Hospital — Lexington, Kentucky, United States
Full record on ClinicalTrials.gov
Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.