An RCT Comparing Xenograft and Allograft for Ridge Preservation
Completed · Not applicable
Conditions studied: Tooth Loss
In brief
To compare the effectiveness of demineralized freeze-dried bone allograft + cross-linked collagen membrane with xenograft + non-cross-linked collagen membrane for posterior extraction socket ridge preservation.
Key facts
- Study ID
- NCT02330523
- Run by
- McGuire Institute
- People needed
- 40
- Starts
- 2014-04-01
- Expected to finish
- 2015-12-01
- Last updated by the study team
- 2016-02-18
Who can join
Age: 18 and older, up to 70. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Subjects 18 to 70-yrs of age
- Subject indicated for posterior tooth extraction (from 1st premolar to 1st molar) intended for implant placement, with adjacent teeth intact (for stent indexing)
- Subjects with extraction site bony buccal dehiscences at least 1/3 the depth of socket and 1/3 the mesial-distal width of tooth socket
- Subjects will have read, understood and signed an institutional review board (IRB) approved Informed Consent Form (ICF).
- Subjects must be able and willing to follow study procedures and instructions.
You may not qualify if…
- Subjects with a history of any tobacco use within the last six months.
- Subjects with healing disorders (i.e., diabetes mellitus, cancer, HIV, bone metabolic diseases) that could compromise wound healing and/ or preclude implant surgery; or who are currently receiving or have received within two months prior to study entry, systemic corticosteroids, immunosuppressive agents, radiation therapy, and/or chemotherapy which could compromise wound healing and preclude periodontal surgery.
- Subjects taking intramuscular or intravenous bisphosphonates.
- Subjects who have a known allergy or sensitivity to alginate, latex, collagen or acrylic.
- Female subjects who are pregnant or lactating, or who intend to become pregnant during the study duration
- Subjects participating in other clinical studies involving therapeutic intervention (either medical or dental).
- Subjects, who in the opinion of the investigator, for any reason other than those listed above, will not be able to complete the study per protocol.
Where it is running
- Perio Health Professionals — Houston, Texas, United States
Full record on ClinicalTrials.gov
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