Impact of Physical Activity on Biomarker of Aging and Body Composition Among Breast Cancer Survivors Age 65 and Older

Completed · Not applicable

Conditions studied: Breast Cancer, Aging, Physical Activity

In brief

To determine if exercise will affect the increase in p16 expression that is associated with both chemotherapy administration and advancing age.

Key facts

Study ID

NCT02328313

Run by

UNC Lineberger Comprehensive Cancer Center

People needed

134

Starts

2014-10-01

Expected to finish

2019-01-16

Last updated by the study team

2020-04-30

Who can join

Age: 65 and older. Sex: female. Healthy volunteers: not accepted.

You may qualify if…

• Age 65 or older, female
• Histologically confirmed Stage I, II or III breast cancer (if the patient has had more than one breast cancer, then the most recent diagnosis)
• Scheduled to begin an appropriate adjuvant or neoadjuvant chemotherapy regimen as defined by NCCN guidelines (www.nccn.org)
• English speaking
• IRB approved, signed written informed consent
• Approval from their treating physician to engage in moderate-intensity physical activity
• Patient-assessed ability to walk and engage in moderate physical activity
• Willing and able to meet all study requirements.

You may not qualify if…

• One or more significant medical conditions that in the physician's judgment preclude participation in the walking intervention.

Where it is running

• Amy Garrett — Chapel Hill, North Carolina, United States

Full record on ClinicalTrials.gov

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