Postoperative Delirium in Hip Arthroplasty Patients

Completed

Conditions studied: Delirium, Postoperative Complications

In brief

Identification of specific circulating microRNAs and microemboli formation (diagnosed by TC Doppler) in both delirious groups and nondelirious group will be our primary target. Delirium assessment through standardized questionnaires will be done at baseline (day of the surgery - pre operatory), immediately after surgery (in post anesthesia care unit) and then every 12 hours in Day 1 and Day2 after surgery. The investigators will use linear mixed models to describe the change patterns overtime, and compare differences at each time point. Inflammatory biomarkers will be explored overtime as well. The investigators will also explore age effect on cognitive function - cognitive reserve - based on the score of the cognitive test administered at baseline.

Key facts

Study ID

NCT02323984

Run by

Ohio State University

People needed

49

Starts

2014-01-01

Expected to finish

2016-03-01

Last updated by the study team

2017-01-20

Who can join

Age: 30 and older, up to 80. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Male or female, between 30 and 80 years of age
• ASA I , II or III
• Capable and willing to consent
• Participants literate in English language

You may not qualify if…

• ASA IV or V
• Patients with severe visual or auditory disorder
• Illiteracy
• Presence of a clinically diagnosed major psychiatric condition such as bipolar disorder, uncontrolled major depression, schizophrenia
• Dementia of Alzheimer's type
• Parkinson disease
• Multiple Sclerosis (MS)
• Vascular dementia

Where it is running

• The Ohio State University Wexner Medical Center — Columbus, Ohio, United States

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.