Phenotyping Acute Pain for Discovery Research and Directed Therapeutics
Withdrawn before enrolling
Conditions studied: Post op Pain
In brief
The goal of the current study is to combine existing and new tools for quantifying patient self-report to characterize changes in acute pain. The ability to quantitatively measure self-report provides behavioral pain phenotypes that can serve as the basis for clustering patients into sub-groups based on their self-report of their symptoms, eliminating observer based perceptions of patients' pain.
Key facts
- Study ID
- NCT02322996
- Run by
- East Carolina University
- People needed
- 0
- Starts
- 2018-02-21
- Expected to finish
- 2018-02-21
- Last updated by the study team
- 2018-02-23
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: accepted.
You may qualify if…
- Male and female patients aged 18 and older willing to undergo clinically indicated non-emergent oral surgery for the removal of impacted third molars with local anesthesia
- Indicated for the removal of third molars, at least a minimum of one partial-bony impacted third molar, with a total difficulty score total of not less than 4*
- Communicate in spoken and written English
- Willing to undergo research observation for 4 hours postoperatively and 48 hour follow up visit
- In good health with an ASA status of 1 or 2 by self report and review of medical history
- Self-report of moderate or severe pain on a categorical scale with a minimum of 4 out of 10 on the numerical rating scale following the offset of local anesthesia
- 1=erupted, 2=soft tissue impaction, 3=partial bony impaction, 4=full bony impaction, 5 = unusual surgical difficulty
You may not qualify if…
- Current or history of mental disorder or substance abuse
- Allergy to aspirin, NSAIDS, or sulfonamide
- Pregnant and/or nursing
- History of peptic ulcers and/or GI bleeding
- Concurrent use of agents which may obscure pain report, e.g., alcohol, opioids, benzodiazepines, and depressants, etc
- Chronic use of medications confounding assessment of the inflammatory response or analgesia, e.g., antihistamines, NSAIDS, steroids, antidepressants
Where it is running
- School of Dental Medicine At East Carolina University — Greenville, North Carolina, United States
Full record on ClinicalTrials.gov
Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.