The Strong Brain Study

Completed

Conditions studied: Osteoarthritis, Sarcopenia

In brief

To evaluate operational aspects of studying pre to post surgery/hospitalization changes in the integrity of a major white matter pathways and how these contribute to reductions in the ability to produce forceful muscle contractions.

Key facts

Study ID

NCT02320864

Run by

University of Florida

People needed

18

Starts

2014-07-01

Expected to finish

2017-06-01

Last updated by the study team

2018-04-05

Who can join

Age: 60 and older. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Aged 60 years old or older with no upper limit at time of baseline assessment
• Right handed; restriction due to left-right hemisphere laterality and white matter pathways
• Able to understand and speak English
• Willing to give informed consent

You may not qualify if…

• Any conditions that pose health risk with physical exertion during a strength test as discovered on a medical history (e.g. heart failure, surgical complications etc.)
• Cancer requiring treatment in past 5 years (exception: non-melanoma skin cancer)
• Serious infectious diseases (e.g., self-reported HIV, sepsis)
• Myocardial infarction/ CVA within last six months
• Congestive heart failure (NY stage III or IV)
• Chronic hepatitis
• History of organ transplantation
• Seizure disorders
• History of head trauma resulting in intensive care
• Current diagnosis of alcoholism
• Drug dependence, or a history of major tranquilizer use
• History of major stroke(s)
• Exposure to toxins or neuroleptics
• History of encephalitis
• Neurological signs of upper motor neuron disease, cerebellar involvement, supranuclear palsy, or orthostatic hypertension that causes fainting
• Major Depression or Major Depressive Episode within three months prior to study
• Claustrophobia
• Non-medical bodily metal
• Pace-maker device
• Less than five years of formal education
• Inability to read or write
• Self-reported hearing or vision impairment that interferes with standardized test administration

Where it is running

• Institute on Aging — Gainesville, Florida, United States

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.