The Role of Neural Systems for Emotion Regulation in Coping With Alcohol Craving
Completed · Not applicable
Conditions studied: Alcoholism
In brief
Cognitive Behavioral Coping Skills Therapy (CBCST) is a commonly utilized, evidence-based psychosocial therapy (talk therapy) for alcohol dependence. By identifying the neural mechanisms through which CBCST changes drinking behavior, it may be possible to improve its efficacy. CBCST promotes abstinence by teaching "coping skills" for managing alcohol-related thoughts and emotions. In this pilot study, the investigators examine the neural systems that play a role in the learning of coping skills through CBCST, specifically focusing on the role of emotion regulation systems.
Key facts
- Study ID
- NCT02316574
- Run by
- New York State Psychiatric Institute
- People needed
- 36
- Starts
- 2014-12-01
- Expected to finish
- 2021-01-01
- Last updated by the study team
- 2021-07-02
Who can join
Age: 18 and older, up to 65. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Right-handed
- Meets DSM-V criteria for current Alcohol Use Disorder
- Currently drinking >5/4 or more drinks/day for men/women in the last 28 day, on average, at the time of initial screening visit.
- Current goal of moderating or abstaining from drinking alcohol
- Seeking treatment for Alcohol Use Disorder
- Agree to not seek additional treatment, apart from Alcoholics Anonymous
- English-speaking and able to provide informed consent and comply with study procedures
- Willing to abstain from alcohol completely for 24 hours on 3 separate occasions
You may not qualify if…
- Any current Moderate or Severe substance use disorder, other than alcohol, nicotine or caffeine use disorders.
- Lifetime history of Bipolar Disorder, Schizophrenia or Schizoaffective Disorder
- A diagnosis of any current psychiatric disorder other than Alcohol Use Disorder (e.g. Major Depressive Disorder, Generalized Anxiety Disorder) that in the investigator's judgment might require intervention with either pharmacological or non-pharmacological therapy over the course of the study.
- History of severe alcohol withdrawal (e.g. seizure, delirium tremens, multiple detoxifications or ER visits for alcohol withdrawal)
- Significant risk for suicide or violence
- Legally mandated to receive treatment
- Sufficiently socially unstable as to preclude study participation (e.g. homeless).
- Currently taking any psychotropic medications.
- Significant cognitive impairment
- Neurological or medical conditions that would interfere with MRI scanning (e.g. history of stroke, seizure, brain tumor, brain infection, multiple sclerosis, metal device in body, pregnancy, claustrophobia)
Where it is running
- NYPInstitute — New York, New York, United States
Full record on ClinicalTrials.gov
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